According to the CIA, the world’s most powerful drug syndicate can be found in Sinaloa, Mexico. After the Colombian cartels were overthrown in the early 1990s, Mexican gangs have gained control over the entire drug supply chain from the plantations all the way to the dealers on the street.
In the 1980s Medellin, Colombia was considered one of the most dangerous cities in Latin America. Pablo Escobar ran his drug cartel from this location and made millions of dollars yearly from drug trade and other illegal activities.